January 21, 2025
After being processed by ultra-micronization, the particle size of traditional Chinese medicine is more fine and uniform, so the specific surface area increases the porosity increases, the adsorption and solubility are enhanced, and the drug can be better dispersed and dissolved in gastric juice, increasing the contact area with gastric mucosa, thus it is easier to be absorbed by the gastrointestinal tract, greatly improving the bioavailability. A considerable part of mineral medicinal materials are water-insol substances, and after being processed by ultra-micronization, the particle size is greatly reduced, which can accelerate their dissolution and absorption in the body, and improve absorption.
The application advantages of traditional Chinese medicine superfine grinding equipment in traditional Chinese medicine production
1. Increase the absorption rate of drugs.
2. Improve dissolution speed and dissolution rate of effective components of drugs.
3. Change the preparation process of traditional Chinese medicine and improve the extraction rate of traditional Chinese medicine.
4. The efficacy, reduce the dosage of drugs, and save raw medicinal materials.
Therefore, the smaller the particle size of the drug, the larger its specific surface area, and the more conducive it is to the dissolution of the ingredients of the drug. The ultra-fine powder has a small particle size, a large porosity, and a large contact area with the gastrointestinal mucosa. At same time, it has a large adhesion force and firmly adheres to the mucosa on the inner wall of the stomach and intestines, which makes it stay the stomach and intestines for a longer time, absorb more fully, and increase the amount of absorption, thus greatly improving the bioavailability of the drug. Whether it an external patch or an oral capsule, it can achieve the efficacy of the original prescription with a smaller dose after ultra-fine crushing.
